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In the SGZ, radial glia-like or type 1 cells—adult multipotent NSPCs— also exhibit a multistep differentiation process as described for the SVZ niche, beginning with the expansion of type 2a cells (transient amplifying progenitor cells) (Seri et al., 2001
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Previous experiments using fractionated cell lysates pointed in this direction 22,23 , but with TRaQ-G probes, it is now possible to monitor these changes in real time and with single-cell sensitivity
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