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Relamorelin, a ghrelin receptor agonist, accelerated gastric emptying in phase 2 trials of diabetic gastroparesis, offering a plausible translational option for SSc [84]
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The ChEMBL drug registry records tirzepatide at maximum phase 4 (approved), first approval 2022, parenteral, with a first-in-class GIP-agonist designation and a boxed-warning flag
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