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More studies should be conducted to investigate whether the observed increases in cytokines IFN-γ, TNF-α, IL-2, and decrease in IL-10 found in granuloma supernatants is indeed the cause of the decreased burden of mycobacterial
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Still, they are also a result of “mitochondrial dysfunction,” which occurs when mitochondria lose the protection of GSH, free radicals attack the mitochondria, and cellular energy decreases.8 Autoimmune conditions like multiple sclerosis, Crohn’s disease, rheumatoid arthritis, diabetes, Lyme disease, heavy metal load, organotoxins, and more all have “mitochondrial dysfunction,” low levels of GSH, and profound fatigue