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Using magnetic resonance imaging (MRI) technique, it could be demonstrated that muscle disruption after strenuous exercise was reduced by daily intake of 2 g l-carnitine compared to placebo [58,61]

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Immunostaining for glial fibrillary acidic protein (GFAB, a marker for astrocytes) and ionized calcium-binding adapter molecule 1 (Iba-1, a marker for microglia) indicated reduced astrocyte and microglia activation in both striatum and substantia nigra