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Too much benzyl alcohol or substitution with other alcohols (ethanol, isopropanol) can directly denature the peptide, especially peptides with significant secondary structure
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In animal models, targeting lactate metabolism (such as inhibiting LDHA or B7-H3) significantly suppresses tumor growth and activates tumor-infiltrating CD8 + T cells, providing a new strategy for combined immunotherapy (98) ( Figure 2 )
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