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For vascular dementia, the 2019 Cochrane review pooled six trials and 597 patients and was more encouraging on benefit: a moderate improvement in cognition, a standardized mean difference of 0.36 (0.13 to 0.58), and a benefit on global clinical function, a risk ratio of 2.69 (1.82 to 3.98) (Cui et al., Cochrane 2019)
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