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[718] Section 6001(a) of the Affordable Care Act effectively eliminated the exceptions for physician ownership in hospitals, although hospitals with physician ownership and a Medicare provider agreement on December 31, 2010, are “grandfathered” to continue using the rural provider exception, if applicable, and whole hospital exception
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Mechanistically, the peptide perturbs the FOXO4 interaction with p53, which selectively causes p53 nuclear exclusion and cell-intrinsic apoptosis (Figure 2, this novel senolytic did remove cells from the PDL9 chondrocytes, which was accompanied by significantly reduced levels of SA-β-gal staining
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