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In the most immediate period after injury induction (skin defect) (i.e., 2, 5, and 10 min), BPC 157 increases Akt1, Braf, Egfr, Egr1, Grb2, Hdac7, Kras, Mapk1, Mapk3, Mapk14, Nos3, Pik3cd, Plcg1, Prkcg, Ptk2, Pxn, Src, Srf, and Vegfa gene expression in rats’ excision wounds in the skin
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Patients with a history of cancer, or those with elevated cancer risk, should approach peptide therapy with particular caution and only under close medical supervision
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